Zovirax Drug Uses
Zovirax is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes healing. Topical Zovirax does not prevent the recurrence of sores but may decrease pain and itching if applied when the earliest symptoms first appear. Oral Zovirax decreases the frequency and severity of recurrent sores, but it is used only by people with severe herpes infections because of possible adverse effects. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How Taken
Treatment with Zovirax topical should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters).
Wash your hands before and after applying Zovirax topical.
Wear a glove or a finger cot or use an applicator (e.g. cotton swab) when applying Zovirax topical to avoid spreading the virus to other body parts and to other people.
Apply enough ointment to cover the lesion(s) completely. A one-half inch ribbon of ointment should cover approximately 4 square inches of surface area.
Avoid getting this medication in the eyes.
Zovirax topical is usually applied every 3 hours, six times a day for seven days. Follow your doctor's instructions.
Use Zovirax topical for the full amount of time prescribed, even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.
Zovirax Warnings/Precautions
Before using Zovirax topical, tell your doctor if you have any other medical conditions or if you use any other medications.
Zovirax topical is in the FDA pregnancy category C, which means that it is not known whether it will harm an unborn baby. Do not use Zovirax topical without first talking to your doctor if you are pregnant.
It is not known whether Zovirax topical passes into breast milk. Do not use Zovirax topical without first talking to your doctor if you are breast feeding a baby.
Zovirax Missed Dose
Apply it as soon as you remember and apply further doses at your regular interval (e.g., every 3 hours) until you go to bed. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Zovirax Possible Side Effects
No serious side effects are expected during treatment with Zovirax topical. If you suspect an allergic reaction (difficulty breathing; rash; hives; itching; swelling of your lips, tongue, or face) seek emergency medical attention.
Other less serious side effects may be more likely to occur. Continue to use Zovirax topical and talk to your doctor if you experience itching, stinging, burning, or a rash. These side effects should resolve quickly.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Zovirax Storage
Store below 25oC. Do not refrigerate.
Zovirax Overdose
An overdose of this medication is not likely to occur. If you suspect an overdose or ingestion of Zovirax topical, call an emergency room or poison control left for advice.
More Information
Zovirax Cream is contra-indicated in patients known to be hypersensitive to acyclovir or propylene glycol.
Zovirax is most effective if it is started within 48 hours of when the rash first appears.
Follow the directions for using Zovirax provided by your doctor.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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The FDA has approved the drug Famvir as the first and only one-day antiviral treatment for recurrent genital herpes and cold sores in people with healthy immune systems.
The drug’s maker, Novartis Pharmaceuticals Corp., announced the FDA approval in a news release dated July 28.
At least 45 million people age 12 and older in the U.S. have had a genital herpes infection -- or about one in five in that age range, says the CDC.
Before, genital herpes required five days of Famvir treatment -- although at a lower dose. Famvir was not FDA approved for cold sores in people with healthy immune systems (meaning those without aids).
The new approval shortens Famvir treatment to a single day at the start of an outbreak and adds cold sores to the drug’s approved uses.
What’s Your Risk for Genital Herpes?
Famvir Dosage
Patients would take 1,000 milligrams of Famvir twice daily for one day at the first sign of genital herpes symptoms, and 1,500 milligrams of Famvir once for one day at the first sign of cold sore symptoms to shorten outbreaks and reduce symptoms.
The drug, available only by prescription, is taken orally.
It does not cure genital herpes or cold sores. Currently, there is no cure for herpes. Antiviral drugs such as Famvir, Zovirax and Valtrex can only help treat or suppress the infection.
Famvir earned FDA approval in 1994 and is used to treat shingles, as well as the herpes virus which causes both genital herpes and cold sores.
Vaginal Gel Blocks HIV, Herpes
Timing Counts
Single-day Famvir should be started within six hours of the first sign of symptoms, such as tingling, itching, burning, or the appearance of herpes sores, says Novartis.
There is “a narrow window of opportunity for treatment” at the start of an outbreak of herpes or cold sores, says Novartis.
Timing is crucial because the virus copies itself most actively in an outbreak’s first hours. Interrupting that process may shorten the outbreak and reduce its severity.
Get the Facts on Sexually Transmitted Diseases
Herpes Virus
There are two types of the herpes simplex virus: herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2).
Cold sores are typically caused by the former, which can spread by kissing an infected person or sharing eating utensils, towels, or razors.
Genital herpes is a sexually transmitted disease (STD) and is usually caused by HSV-2, although it can result from HSV-1.
Most genital herpes patients have few or no symptoms, the CDC notes.
When symptoms appear, there are usually one or more blisters around the genitals or rectum. The blisters can break, leaving tender sores that may take several weeks to heal.
Clinical Trials
Single-day Famvir was tested in clinical trials for treatment of recurrent genital herpes and cold sores.
The genital herpes trial included 329 patients. At the first sign of a herpes outbreak, they got one of two treatments, without knowing which they received:
1,000 milligrams of Famvir twice daily for one day A pill containing no medicine (placebo).
The Famvir group had milder symptoms and shorter outbreaks that lasted about four days, instead of six days with the placebo, Novartis reports.
Single-dose Famvir had a similar effect on the length and severity of cold sores in the cold sores trial, which included 481 patients, according to Novartis.
Novartis is a WebMD sponsor.
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