Paxil Drug Uses

Paxil is an agent in a newer class of antidepressant medication known as selective serotonin reuptake inhibitors (SSRIs). Depression and anxiety disorders might be caused by a chemical imbalance in the brain. One of these chemicals is serotonin, which helps send electrical signals from one nerve cell to another. In the process, serotonin is released from one nerve cell (the sender) and travels to the next (the receiver), where it is either absorbed or returns back to the original sender cell.

How Taken

Paxil comes as a tablet to take it orally. It is usually taken once daily and may be taken with or without food. Do not take more or less of it or take it more often than prescribed by your doctor. Continue to take Paxil even if you feel well. Do not stop taking Paxil without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

Paxil Warnings/Precautions

Before taking Paxil, tell your doctor if you have liver disease, kidney disease, seizures or epilepsy, or a manic disorder or suicidal thoughts. You may not be able to take Paxil, or you may need a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Paxil is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take Paxil without first talking to your doctor if you are pregnant or could become pregnant during treatment. Paxil passes into breast milk and may affect a nursing baby. Do not take Paxil without first talking to your doctor if you are breast-feeding a baby.

Paxil Missed Dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Paxil Possible Side Effects

If you experience any of the following serious side effects, stop taking Paxil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); an irregular heartbeat or pulse; low blood pressure (dizziness, weakness); high blood pressure (severe headache, blurred vision); unusual bleeding or bruising; or fever or chills. Less serious side effects may be more likely to occur. Continue to take Paxil and talk to your doctor if you experience headache; tremor, nervousness, or anxiety; nausea, diarrhea, dry mouth, or changes in appetite or weight; sleepiness or insomnia; or decreased sex drive, impotence, or difficulty having an orgasm. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Paxil Storage

Store at controlled room temperature between 20-25°C (68-77°F).

Paxil Overdose

Seek emergency medical attention if an overdose is suspected. Symptoms of a Paxil overdose include nausea, vomiting, tremor, seizures, agitation, drowsiness, hyperactivity, and enlarged pupils.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Paxil may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness or dizziness while taking Paxil.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Dr. Peter Schlegel of the Cornell Medical Center in New York, along with a colleague, recently treated two men for infertility and found when both patients stopped taking their prescription antidepressant medications -- selective serotonin reuptake inhibitors (SSRIs) -- their sperm counts dramatically increased. Schlegel then observed that when both men re-started their antidepressants, their fertility problems returned.
One patient was taking citalopram -- sold as Cipramil -- and the other was on sertraline, sold as Lustral. The second patient switched to venlafaxtine -- Effexor -- and again his sperm count dropped to near zero. Schlegel believes that because SSRI drugs affect both sperm count and the ability of sperm to move, the antidepressants may be preventing sperm from reaching the semen.
"The patients had normal sperm counts and motility before medication," Schlegel said. "On the medication they have deterioration of both. The same patients going on and off medication had the same pattern. It shows a strong association."
The U.S. Food and Drug Administration required most SSRI drugs to carry the agency's strongest "black box" warning in 2004 for their association with increased risk of suicide. Other common side effects of the drugs include impotence and delayed ejaculation.
Allan Pacey, senior lecturer in andrology at the University of Sheffield, said, "There does seem to be a major correlation. Maybe this is an unknown side effect of these drugs that is only just coming to light."
Schlegel's study linking low sperm count to SSRI drug use noted that an additional dozen patients reported similar effects from the antidepressants. Because of the small number of patients involved, the study's implications need verification, Schlegel said. A clinical trial involving 30 male patients taking sertraline has begun to bolster Schlegel's findings.
The researchers warned that men taking SSRIs to treat mental disorders, who are concerned about low sperm counts, should not alter their drug use without consulting a qualified medical professional.

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