Evista Drug Uses
Evista is a prescription medicine used by women after menopause to treat or prevent a condition called osteoporosis. You should take calcium and vitamin D along with Evista if you do not get enough calcium and vitamin D in your diet.
How Taken
The recommended dosage is one 60-mg Evista tablet daily, which may be administered any time of day without regard to meals.
Evista Warnings/Precautions
Before taking this medication, tell your doctor if you have a history of blood clots; stroke; cancer; increased triglycerides (a type of fat in the blood); or liver disease.
You may not be able to take Evista, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Evista is in the FDA pregnancy category X. This means that Evista is known to cause birth defects in an unborn baby. Do not take Evista if you are pregnant or if you could become pregnant during treatment.
It is not known whether Evista passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
Evista Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
Evista Possible Side Effects
An infrequent but serious side effect of taking Evista is the development of blood clots in the veins. These blood clots can stop blood flow and cause serious medical problems, disability or death. Call your doctor right away if you have or have had any of the following signs of blood clots in the legs, lungs or eyes: leg pain or a feeling of warmth in the calves, swelling of the legs, hands or feet, sudden chest pain, shortness of breath or coughing up blood, sudden change in your vision, such as loss of vision or blurred vision.
Most of the side effects of Evista are mild and usually do not cause women to stop taking Evista. The most common side effects of Evista are hot flashes and leg cramps. Hot flashes are more common during the first 6 months after starting treatment.
If you have any problems or questions that concern you while taking Evista, ask your doctor or pharmacist for more information.
Evista Storage
Store at controlled room temperature, 20o to 25oC (68o to 77oF); allows excursions between 15o and 30oC (59o and 86oF).
Evista Overdose
Incidents of overdose in humans have not been reported. There is no specific antidote for Evista.
More Information
Before having any surgery, tell your doctor that you are taking Evista. Treatment with Evista may need to be stopped temporarily if you require an extended period of bed rest.
Avoid sitting still for long periods of time during travel while taking Evista.
Alcohol and cigarette smoking may cause increased bone loss. Discuss with your doctor the use of these products.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Estrogen injections might help keep women's minds sharp as they age, a new study of female monkeys suggests.
For the study, published in this week's online issue of the Proceedings of the National Academy of Sciences, researchers at Mount Sinai School of Medicine, in New York City, removed the ovaries of four distinct groups of female rhesus monkeys. One group included old monkeys that received estrogen; a second group included old monkeys that did not receive estrogen; and there were two other groups of young monkeys that either received or did not receive estrogen.
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Removing the monkeys' ovaries induced menopause. The older monkeys had their ovaries removed around the time of perimenopause -- before the onset of full menopause.
Estrogen treatment involved pure estradiol injections every 21 days. The researchers periodically tested the monkeys on a series of cognitive tasks over the course of more than two years.
Older monkeys that were treated with estrogen performed almost as well as the younger monkeys on the mind-challenging tests, the researchers reported, while untreated older monkeys showed dramatic cognitive declines.
Surprisingly, the younger monkeys performed equally well whether or not they were treated with estrogen.
The study also found that the estrogen-treated monkeys showed brain changes associated with the prevention of cognitive decline. On the other hand, the older untreated monkeys showed no signs of these changes.
The findings suggest that the debate over whether hormone replacement therapy is beneficial may not be over, according to study co-author John H. Morrison, dean of basic sciences and the graduate school of biological sciences at Mount Sinai.
"There's been a great deal of confusion as to whether estrogen helps or harms postmenopausal women, and our findings tell us is that there is a very critical window of opportunity in which estrogen may be helpful," he said in a prepared statement.
He noted that this critical window could be around the time of perimenopause, when estrogen may be able to protect the brain from cognitive decline.
"Estrogen levels decline in old age, so the brain may need a certain amount of circulating estrogen to remain supple. Timing may be everything," Morrison said.
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